home technology applications about us news
deltaDOT is a spin out company from Imperial College London UK - a team of scientists and  engineers dedicated to the advancement of analytical techniques using patented methods and  instrumentation in High Performance Capillary Electrophoresis (HPCE). We design and  produce HPCE instruments which we are marketing worldwide. We also use the same  instruments to offer Analytical Services and Contract Research. Our offices and laboratories  are based in the London Bioscience Innovation Centre (LBIC). 
Who we are 
HPCE instruments 
High Performance Capillary Electrophoresis (HPCE) analytical instruments are designed,  manufactured and marketed by deltaDOT. These instruments use deltaDOT’s proprietary  imaging and analysis technology called Label Free Intrinsic Imaging (LFII®). High  Performance Capillary Electrophoresis and Label Free Intrinsic Imaging applied to a CE  analytical system  offers dramatically improved discovery power in comparison to other  conventional CE systems.
deltaDOT’s team of scientists has developed a considerable expertise in CE based analysis  and in solving clients’ analytical problems. Using our own HPCE LFII® analytical instruments  we also offer Analytical Services, Contract Research and Scientific Collaboration to industry  and academia from our laboratories at the London Bioscience Innovation Centre. Our recent  and current collaboration examples include those shown below. 
Analytical Services Contract Research Scientific Collaboration 
HPCE Applications 
High Performance Capillary Electrophoresis (HPCE) is applied in Life Sciences research, drug  testing, diagnostics and bio-pharmaceutical manufacturing. This technology is used in  detection, separation and analysis of proteins, nucleic acids, carbohydrates, viruses and  bacteria, chemicals and a wide range of other analytes. More detail can be found on our  Technology pages. 
Application Notes Downloads Quick Update 
Antibody Analysis, Amino Acid Analysis, Transferrin, Small Molecules, Peptides, Complex Protein Lysates, Recombinant Human Erythropoietin, Antibiotics in food products, Glycoforms, DNA, RNA, Chemicals, Baculovirus Titre. Glomerular filtration rate (GFR) determined by Iohexol clearance was developed in  collaboration with Royal Veterinary College for renal failure diagnosis in companion animals  (...more) 
20 Sep 2016 National Health Service Quality Control North West (QCNW) Liverpool  labs  presented the data on monoclonal antibody stability trials based on deltaDOT’s Capillary  Electrophoresis (CE) technology  and expertise. They state that CE technology is suitable for  monitoring the stability of monoclonal antibodies and can perform purity and charge analysis  with high resolution and repeatability. They conclude that CE can replace other techniques  commonly used for this analysis IEC and SDS PAGE (link to the poster).  3rd July 2016 Monoclonal Antibody Stability Trials using deltaDOT HPCE-512 technology  reported by Dr. Deepika Devanur. Now available in pdf slide format on our website (...more)  4th March 2016, FDA CFR21/11 Compliance - deltaDOT’s progress continues with the  implementation of the software qality system while the P3 controller system management  software and the P3EVA analysis package had their compliance completed previously  deltaDOT engineers are working with Optra systems of California (...more)  26th January 2016, National Health Service Quality Control North West (QCNW) Liverpool  Labs are to perform monoclonal antibody stability trials, utilising deltaDOT Ltd technology  and expertise to aid the study     4th February 2016 Webinar: Improve your Monoclonal Antibodies Analysis. Live webinar  on analysing mAbs from production to patient. Given jointly by Horiba Scientific and  deltaDOT Ltd. Presented by Dr. Deepika Devanur (...go to registration site)  14th December 2015, deltaDOT technology used to define product quality for ImmBio  Ltd. deltaDOT Ltd (London) are pleased to announce that its Label Free Intrinsic Imaging  (LFII®) technology has been used to help ImmBio (Cambridge UK) to submit an  Investigational Medicinal Product Dossier (IMPD) as part of a clinical trial application to The  Medicines and Healthcare products Regulatory AgencMHRA (...more)  24th  November 2015, NW Labs are to market a kidney function test developed by  deltaDOT Ltd and the Royal Veterinary College. At the London Vet Show held at Olympia  on 19 and 20 Nov 2015 it was announced that NW Labs are now promoting deltaDOT’s  Glomerular filtration rate (GFR) assay for measuring kidney function in cats and dogs. NW  Labs will refer cases of suspected early stage renal disease for measurement by deltaDOT  with interpretation and advice on management by expert clinicians at the Royal Veterinary  College, London (...more) 12-14 March 2015, 2nd International Conference on Label-Free Technologies  Boston Marriott Cambridge, MA, USA. Dr. Stuart Hassard will be speaking on Label free  intrinsic imaging high performance capillary electrophoresis - a powerful tool in analytical  science. 4th, 5th March 2015 Keeping pace - Analytics for tomorrow’s biopharmaceuticals    conference, Leeds, UK. Dr. Stuart Hassard will be speaking on Label free intrinsic imaging  high performance capillary electrophoresis trends throughout biopharmaceutical process  analytical technology.  21st October 2014 deltaDOT CSO Dr. Stuart Hassard to co-Chair BBSRC  Strategic Tools  and Resources Development Fund committee in November. 18 October 2014 deltaDOT’s Label-free HPCE-512 - a key instrument in accurate analysis of  drug-antibody complexes (DAR); see a recent Paper “Next generation maleimides enable  the controlled assembly of antibody–drug conjugates via native disulfide bond bridging”